Addition of fentanyl to prilocaine for intravenous regional anaesthesia

REGIONAL ANAESTHESIA Autonomic effects of epidural and intravenous fentanyl

Methods. Ten volunteers were anaesthetized with desflurane. Noxious stimuli of variable intensity were then delivered by tetanic electrical stimuli. Heart rate, arterial pressure, and pupillary dilation in response to these stimuli defined nociception. Seven of these volunteers participated twice using a crossover design: they received i.v. fentanyl on one study day and epidurally on the other....

Influence of the addition of potassium to 0.5% prilocaine solution during I.V. regional anaesthesia.

Six volunteers underwent i.v. regional anaesthesia on two occasions using 0.5% prilocaine 40 ml with potassium 0 or 4 mmol litre-1. Addition of potassium produced more rapid sensory blockade to pinprick at five of the six sites tested, although this was statistically significant at only one site (P less than 0.05) and more rapid sensory blockade to pinch with Allis forceps at four of the six si...

Comparison of the disposition kinetics of lidocaine and ( ± )prilocaine in 20 patients undergoing intravenous regional anaesthesia during day case surgery

Comparison of the disposition kinetics of lidocaine and (+/-)prilocaine in 20 patients undergoing intravenous regional anaesthesia during day case surgery.

OBJECTIVE The aim of this investigation was to compare the pharmacokinetics of lidocaine and prilocaine in two groups of 10 patients undergoing intravenous regional anaesthesia. METHOD The study had a randomized design. The patients were allocated to one of the two groups of 10. Each group received either lidocaine (200 mg = 0.855 mM) or prilocaine (Citanest, 200 mg = 0.909 mM), injected intr...

Comparison of intrathecal fentanyl and diamorphine in addition to bupivacaine for caesarean section under spinal anaesthesia.

BACKGROUND Co-administration of small doses of opioids and bupivacaine for spinal anaesthesia reduces intraoperative discomfort and may reduce postoperative analgesic requirements in patients undergoing Caesarean section. Fentanyl and diamorphine are the two most frequently used agents in UK obstetric anaesthetic practice. METHODS Seventy-five healthy parturients scheduled for elective Caesar...